In these mice, mice lose only about 2 percent of their weight a week. The study authors also reported the potential for such mice to be used to treat “a number of life-threatening medical conditions” like hemophilia and stroke. We’ll leave you to ponder about the use of CRISPR’s for those patients.
The study itself is a pretty big story . The mice in question were treated for just a few days and were then put on CRISPR-Cas9/crd20 combination for six weeks. As expected, their body weight decreased by approximately 5 percent, as expected. However, it was noted that their fat content did change within the study period. “Over time, the fat massdisappeared , a finding that supports the role of these engineered cells in shaping the fat depots of mice.” So this is, at least from my own experience, a fairly safe thing to do to your own pets. (The mice in question weren’t treated with CRISPR/Cas9/crd20 for the entire six weeks of the study, so those changes may not have been present during the months after being treated, which is why the mice were tracked.) After this short stint on CRISPR-Cas9/crd20, the other mice in the study were put on a longer treatment, followed by their body weight becoming normal. That’s about as far as you can go with reducing the amount of body weight. I would imagine, however, that you could just as well do things that cause mice’s fat cells to become obese just to make sure they go away, so the real question here isn’t “if” but “why” these mice lost all that fat, rather than just some kind of genetic change. (Of course, if you take mice and train them to lose fat and go on an extremely low calorie diet, there’s always a chance of genetic changes.) The same study suggests that CRISPR/Cas9/crd20 may have even greater results in people. We’re not talking about the fat loss itself, thoughin order for a cureto work, its usually required that the patient be very sick, meaning one where there’s literally no other medical option. This new study was a collaboration between two very importantresearch efforts. One is from researchers at the University of Oxford who originally created CRISPR/Cas9as a way to use DNA to identify a few specific genes in people. The other is from researchers at CRISPR Genetics in Lausanne Switzerland, who developed CRISPR/Cas9/Crd20 combination as a way to use DNA to edit proteins on a cell’s surface.
We’ll discuss the latter later. For now, though, let’s focus on the first, which is the team from the University of Oxford. They originally used CRISPR/Cas9/Crd20 combination to create mice that were highly capable of expressing certain immune genes. They then tested different combinations, and found that CRISPR/Cas9 combinations (which, like the C. elegans, they named CRISPR1/5 andCas9/Ccl20) could achieve better immune responses than combinations using only the proteins that are normally expressed by the immune system. The researchers hypothesized that CRISPR1/5/Cas9 combinations could reduce the body’s response to bacterial infections by inducing the destruction of the bacterial cell and the destruction of the bacterial cell’s surface antigen, the part of the cell that would normally contain a bacterial marker. This would also cause the cell’s surface antibody proteins to be produced more rapidly. The team further hypothesized that this would also help the body to eliminate infected cells, since the antibody-generated destruction and destruction of the bacteria-containing part of the cell would be enough to remove that cell while the immune system would be unable to recognize it.
The researchers believe that the immune system would prefer to target this part of the bacteria, instead of the one containing the dangerous genetic material. Now, what did the researchers test? They first tested CRISPR/Cas9/Ccl20 with mice that lacked a specific type of melanoma gene called BMP2, but only after they had injected them with melanogenic stem cells that had the proper BMP2. In other words, the stem cells were made of melanina pigment found naturally in human skin. After a few weeks of injecting the cells, the researchers found that their mice were able to destroy non-melanoma skin cells, which is a pretty impressive find, considering they failed to give anything to the mice other than the non-melanomas, which are normal forms of skin. In fact, after many weeks of this kind of treatment, the researchers observed that the animals were able to destroy non-melanoma skin cells even