Stimulant-dependent regeneration is currently widely considered to be the key of spinal cord injury. However, a further step may be the involvement of non-stimulant components of the spinal cord in pain regulation.
The lack of clinical evidence demonstrating evidence for the efficacy of stimulators in the treatment of spinal cord injury suggests that new treatments are needed across the entire industry. (ApiPharm.com, “Stimulant-effect-specific” and “Numerous reports on the pharmacological effects of amphetamines and their potential therapeutic applications, including analgesia”, August 20, 2003 )
 Stimaurs et al., “Effects of Stimulant Interactions on the Brain.” Scientific Reports (July 27, 2003) by
Dianne Vollmer et al., “Lack of studies investigating the effects of stimulants on the neurogenesis and function of the substantia nigra and hippocampus”, Neuroendocrine Pharmacology (June 21, 2002)
Further research is needed to determine if stimulants alter the biological actions and prognoses of both spinal cord and motor system. The following findings were presented:
Pulmonary health: Intestinal health: Cerebrospinal fluid leakage to the rectum: Vascular health: Cerebrospinal fluid is leaking into the rectum, resulting in inflammation to the glenohumeral tract, and brain damage. The kidneys are often the leading tissues of the brain. (Dianne and J.M. Hsieh, Brain and Behavior, 3(5), 2000)
Overall however, there is no clear clear evidence to support a beneficial effect of stimulants on health. What we do know is that, despite the scientific evidence for stimulants and the benefits of these stimulants, no specific studies have been done to address the long-standing concern. The current paradigm is not looking to address the long-standing anxiety and depression and behavioral problems and has been abandoned for new treatments like anti-anxiety drugs that use selective serotonin reuptake inhibitors.
However, there is still work within the field of neurological research (particularly neurology for ADHD). We know a lot about what happens in the frontal cortex during sustained exposure a part of the frontal and parietal cortex that works like a trigger for memory and attention in humans. A large part of this work is done in relation to the hippocampal thalamus.
In fact, ADHD is a very common problem in the context of brain development and has been hypothesized to be caused by the lack of good memory and attention. Focusing on our present research however, is actually kind of depressing. While it is possible that a much more recent case may be seen with stimulants, the current study that we are in is probably the first one that we are having any good experience with the clinical effects of stimulant use.
The fact that even if they did address the long-standing concern, then who knows what would happen if we all had the same negative experience? What makes it so difficult to get people to stop using stimulants is that they can do more harm than good if we all stopped using the same drugs. A large study led by Stimaurs showed that chronic use of stimulants in the first few months of life resulted in a loss of muscle tone leading to an increase in the frequency of spasticity.
As my wife, Dr. L.A. Toh and I both commented at the beginning, “Stabbing is something that our children have in every sense of the word, but don’t need to deal with. We now have the evidence to say that if you are a stimulant addict but you remain on the drugs at night, there is nothing to stop you,” so that is an approach that we’re still just leaving behind.”